Anti-plasmodial activity of Ailanthus excelsa

Anti-plasmodial activity of Ailanthus excelsa.

The anti-plasmodial activity of Ailanthus excelsa stem bark was investigated. The methanolic extract inhibited in vitro growth of chloroquine-sensitive (D10) and resistant strains (W2) of Plasmodium falciparum (IC50 4.6 and 2.8 microg/ml, respectively). The effect was retained in the chloroform fraction (3.1 and 2.1 microg/ml, respectively). The anti-plasmodial activity could be ascribed to the...

Acute - Toxicity, Anti-Inflammatory and Anti-Diarrhoeal Activity of Ailanthus excelsa in Mice and Rats

Ailanthus excelsa (Stem bark) are used in folk medicine for a treatment of inflammation, arthritis, expectorant, stimulant and asthma. Acute toxicity study of A. excelsa stem bark was performed on mice (Swiss) and albino rats (Wistar strain),given single doses 1,10, 50, 100 ,1000 and 2000mg/kg,po. showed normal behavior and no mortality up to 14 days except 500,1000 and 2000mg/kg dose 20%, 60.0...

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Anti-allergic and Anticataleptic Activity of Aqueous Extract of Leaves of Ailanthus Excelsa Roxb

The anti-allergic of an aqueous extract of the leaves of Ailanthus excelsa Roxb.(AELAq) was evaluated by using milk induced leucocytosis and eosinophilia in mice, passive paw anaphylaxis in rats models while the anticataleptic properties was evaluated by Clonidine induced catalepsy in mice mode. The extract significantly (*p<0.05, **p< 0.01) decreased the leucocytosis and eosinophilia along wit...

In vitro Anti Plasmodial Activity of Enicostemma littorale

Problem statement: Malaria is a prevalent disease in India. The problem of drug resistance is worsening. Hence, new effective and affordable antimalarial drugs are very much needed. The long-established use of quinine and the more recent introduction of artemisinin as highly effective anti malarials demonstrate that plant species are an important resource for the discovery of new anti malarial ...